A patient underwent a TAHBSO with a final pathologic diagnosis of endometrial adenocarcinoma. What would be assigned to Pathological Grade?

In the context of endometrial adenocarcinoma, the pathological grade is determined based on the characteristics of the tumor cells observed under a microscope. The grading system for endometrial cancer typically involves assessing the degree of differentiation of the tumor cells.

A grade of 1 indicates well-differentiated tumor cells, meaning that the cancer cells appear more like normal cells and are usually associated with a better prognosis. This level of differentiation suggests that the tumor is less aggressive and likely to have slower growth. Thus, if the final pathologic diagnosis indicates a grade of 1, this implies that the tumor has well-defined characteristics that align with a less severe form of endometrial adenocarcinoma.

In comparison, grades 2 and 3 would represent moderately differentiated and poorly differentiated tumors, respectively. A grade of 9 is typically used for cases where the grade is not assessed or cannot be determined. Therefore, assigning a pathological grade of 1 means the tumor is well differentiated, which is the reason this option is correct.