Acromegaly is characterized by what physical change?

Acromegaly is a hormonal disorder that results from an excess of growth hormone, typically due to a benign pituitary tumor. One of the most distinctive physical changes associated with acromegaly is the enlargement of the extremities. This condition leads to a gradual and notable increase in the size of hands and feet, as well as broader facial features, which often includes a protruding jaw and enlarged nose.

The characteristic enlargement occurs because the excess growth hormone stimulates the growth of bones and soft tissues, resulting in noticeable changes over time. These changes can affect not just the extremities, but also other areas such as the skull and facial structure.

Understanding acromegaly helps in recognizing its symptoms early, which is crucial for managing potential complications associated with the disorder. In this context, the other options—excessive hair growth, severe skin irritation, and decreased muscle mass—are not typical characteristics of acromegaly and do not correlate with the underlying pathology of excessive growth hormone.