What does ENE stand for in cancer terminology?

ENE stands for Extranodal extension in cancer terminology. This term refers specifically to the extension of cancer beyond the lymph nodes into the surrounding tissues. In various types of cancers, especially in head and neck cancers, assessing the presence of extranodal extension is critical for determining the tumor's aggressiveness, staging, and subsequently the appropriate treatment plan.

Extranodal extension can indicate a higher risk of metastasis and can influence prognosis, making it an important factor in clinical decision-making. Therefore, recognizing and accurately reporting ENE is vital for cancer registrars and data specialists to ensure correct staging and treatment protocols are applied.