Which histology is NOT reportable according to SEER guidelines?

According to SEER (Surveillance, Epidemiology, and End Results) guidelines, certain histologies are categorized as reportable or non-reportable for cancer registries. In this instance, cervical adenocarcinoma in situ, HPV associated, is indeed reportable due to its significance as a precancerous lesion associated with a defined risk of progression to invasive cancer.

In contrast, the option indicating differentiated exophytic vulvar intraepithelial lesion does not usually meet the criteria for reportable tumors. These lesions generally fall under the category of non-invasive or benign conditions and are not considered malignant despite their dysplastic nature. As a result, they do not require reporting to cancer registries.

Understanding these distinctions is crucial for accurate cancer data collection and analysis, ensuring that only those conditions that meet specific malignant criteria are reported. This practice helps maintain the integrity and relevance of cancer data used in public health and research.